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121 Together, these observations provide evidence for ferroptotic cell death in the livers of mice exposed to a single high-dose combination of rifampicin and isoniazid, as well as in patients treated with these drugs

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Each specimen/sample was examined for abnormalities, including icteric, lipemic, lysis, and turbidity

And then, there are factors that increase the need for glutathione like excessive oxidative stress, poor nutritional status, or increased toxic load that will deplete GSH levels if not sufficiently supported and/or replenished 4