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Using a multi-omics approach, we examined the outcomes of independently knocking down 438 antioxidative stress genes by analysing the Broad Institutes Project Achilles dataset (genome-wide shRNA knockdown in 201 cancer cell lines 16 ) (see Methods)

MW, HW, and YLu were involved in the cell culture and in vitro experiments

These observations are consistent with the hypothesis that enhancement of glycine-dependent signaling may mitigate aspects of NMDA receptor hypofunction, a mechanism widely implicated in the pathophysiology of schizophrenia (Zhang et al

The heritability ( h 2 ) of NE pl , NE u , and GSH ranged from 50 to 70%, and these biochemical quantities were considerably more heritable than BP

Researchers became interested in it after early studies suggested it might promote tissue repair, particularly in the gut, tendons, and ligaments