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The radical scavenger IAC (bis(1-hydroxy-2,2,6,6-tetramethyl-4-piperidinyl) decantionate) decreases mortality, enhances cognitive functions in water maze and reduces amyloid plaque burden in hAPP transgenic mice

The authors suggested that the neutralization of FUS-LCD by N-terminal acetylation may disturb other interactions between the molecules as well as phase separation by changing the peptide net charge from 2 to 3 119

accordingly, restricting fructose availability or inhibiting this metabolic pathway significantly suppresses tumor growth and enhances chemotherapy sensitivity (32)

B12 supports this process indirectly through its effects on homocysteine

As a result, older cells are more susceptible to oxidation