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Cancer 104 (4), 788793

Of note, CD40 is a transmembrane glycoprotein surface receptor, a member of the TNF receptor superfamily, and its activation is associated with increased effectiveness of antigen presentation and the upregulation of major histocompatibility complex class II and costimulatory molecules CD80/CD86

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282 Moreover, IL-22Fc induces MTs in the liver, resulting in decreased hepatic ROS production, stress kinase activation, and inflammatory functions, leading to the amelioration of nonalcoholic steatohepatitis

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