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Furthermore, in ME/CFS, PEM has been associated with defects in the TCA cycle, where a metabolic impairment reduces ATP production and increases lactate accumulation (Nilsson et al., 2020)

At the same time, this should be accompanied by systematic assays to quantify the protection conferred by intervention strategies aimed at gut microbiota (e.g., inhibiting TMA-producing bacteria), targeting the TMA-TMAO metabolic axis or direct scavenge of TMAO on chondrocyte ferroptosis and OA progression

This triggers the final maturation of the oocyte to an ovum (egg) and the generation of an embryo

H.MoreauP.TouzeauC.FaconT.et al (2021)

Yang CS, Suh N, Kong AN