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doi: 10.1038/ejcn.2017.58 212 NiuQWeiWHuangZZhangJYangBWangL

Simultaneously, astrocyte-related lipid metabolism disorders induce lipotoxicity in neurons and hinder the normal physiological function of neurons

Interestingly however, clinical data has shown that lower ACC1 expression is associated with poor survival rates, which may suggest that there is a context-dependent tumor suppressor role for this enzyme in certain populations (68)