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The Stomach Acid Hurdle Stomach acid is designed to break down proteins, and since glutathione is essentially a tiny protein (a tripeptide), the stomach views it as food to be digested rather than a supplement to be absorbed

Thermal treatments and fermentation generally enhance polyphenol release by disrupting cell-wall matrices and promoting the liberation of bound compounds (Ribas-Agust et al., 2019)

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Synergistic integration and challenges in immunotherapy In TC, the immunosuppressive tumor microenvironment is jointly formed by the DNA methylation-metabolism axis, which provides a molecular theoretical basis for combining immunotherapy with epigenetic and metabolic interventions