Correlations between GPs and metabolic syndrome components, lipid and hepatic panels, adiposity, oxidative stress, and inflammation biomarkers Several GPs that showed significant average paired fold changes at the end of 4th week during 4-week intermittent fasting and 1 week after 4-week intermittent fasting were correlated with the components of metabolic syndrome, lipid and hepatic panels and adiposity, oxidative stress and inflammation biomarkers at the end of 4th week during 4-week intermittent fasting (Supplementary Table 4) and 1 week after 4-week intermittent fasting (Supplementary Table 5)
For instance, exposure to PS-MPs has been shown to significantly alter gut flora composition, correlating with decreased oxytocin levels in the medial prefrontal cortex (mPFC) and impaired social behaviors in C57BL/6 murine models (Wang L
The consistent findings across various species and models strengthen the translational potential of this mechanism, providing a foundation for future research aimed at refining therapeutic strategies and highlighting the potential of modulating GLUT1 expression in various disease contexts
In the study, patients who received a second-line treatment of the combination had a median survival of 15.3 months
Translationally controlled tumour protein (TCTP) is a highly conserved and widely expressed protein, and in a recent study, overexpression of TCTP in mouse oocytes was shown to reverse age-associated telomere shortening by increasing telomerase activity [75]