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Employing digital PCR (dPCR) and next-generation sequencing to longitudinally quantify mtDNA mutations in paired peripheral blood, tissue biopsies, and CSF will clarify their roles in residual inflammation, neurocognitive decline, and immunological failure

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doi: 10.1016/j.cell.2016.02.011, Summary Keywords coronary heart disease, gut microbiota, immune environment, metabolites, phenylacetylglutamine Citation Ren B, Wang H, Cao Y, Zhang Z, Wu X, Ji S and Zhao J (2026) Integrated analysis reveals microbiotametaboliteimmune alterations associated with coronary heart disease