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This suggests that the delicate balance between pro-oxidants and antioxidants is crucial, and that the antitumor effect of HTX may involve mechanisms in addition to antioxidant action, possibly related to the modulation of intracellular signaling pathways influenced by hormonal status, especially in hormone-dependent tumors [45,62,98,100,101,103]

At this stage of the experiment, normal mice usually spend most of their time in the chamber containing a novel animal, rather than in the chamber containing an empty box, as they try to identify this novel animal well