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We first examined the SIRT2 expression and GSH levels in a list of human RCC cell lines, and observed a well-correlated expression pattern (Fig

TNFR2/1433 signaling complex instructs macrophage plasticity in inflammation and autoimmunity

Here we used such iPSC-derived complex liver organoids to assess the specific impact of ALGS-causing mutations on parenchymal and non-parenchymal liver cells, their role on bile duct formation and survival, and the interactions between signaling pathways suspected to play a role in ALGS pathophysiology