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If oral B12 supplements are not raising your levels, sublingual or injectable B12 may be necessary to achieve therapeutic levels and start feeling better

doi: 10.1016/j.fct.2013.01.051 563 SinghAPSinghRVermaSSRaiVKaschulaCHMaitiPet al

Continuous Monitoring: Alerting to changes that might indicate compromise

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In summary, TFAM protein abundance is closely related to mtDNA content, and TFAM affects mitochondrial biosynthesis by regulating mtDNA copy number through its interaction with mtDNA (Picca and Lezza, 2015)