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Proline and its derivate hydroxyproline, account for 21 % of the amino-acid residues of the fibrous protein collagen, essential to connective tissue

At the metabolite level, changes were predominant in the catabolism of FFAs and branch-chain amino acids (BCAAs), mitochondrial/peroxisomal and proteasomal protein processing, and the biosynthesis of acetyl-CoA, acyl-CoAs and purine nucleotide bisphosphates

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Topalova-Dimitrova A, Dimitrov IV, Nikolov R

For this experiment, the temperature was maintained at 60 C, as OsDHAR and catalase (CAT) aggregate at this temperature over time (Fig