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Being able to detect up to 830 metabolites with the applied platform (Metabolon), we uncovered hyperglycemia-associated alterations in the tumor metabolome (Supplemental Table 1), as shown by the principal component analysis (PCA

The presenilin-1 E9 mutation results in reduced -secretase activity, but not total loss of PS1 function, in isogenic human stem cells

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Landscape of EGFR -dependent and -independent resistance mechanisms to osimertinib and continuation therapy post-progression in EGFR-mutant NSCLC

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