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Cognitive impairment is present throughout the course of the disorder, from prodromal to more severe stages

High-throughput metabolomics analysis of plasma from patients with PE showed that some biomarkers were significantly enriched in the tricarboxylic acid cycle, fatty acid metabolism (acylcarnitine), and purine metabolism 9

The neuroprotective effects of carnitine have revealed its potential therapeutic value in the treatment of neurological diseases such as autism spectrum disorder, depression, and Alzheimers disease [96, 97]

For instance, a 2017 review showed that taking L-carnitine for 3 days had no effect on markers of brain function including reaction time, vigilance, immediate memory, and delayed recall in young adults without cognitive impairment