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Untreated parasites were taken as control

Interestingly, treatment of DLA bearing mice with MMAE resulted in a dose-dependent increase in MST, AST, % IMLS and % IALS up to 100 mg/kg

These approaches aim to circumvent the aforementioned barriers by increasing curcumins solubility, protecting it from rapid hepatic metabolism, and enhancing its intestinal permeability

Qu, M., Zhou, X., Wang, X

Serious cardiovascular events, QT prolongation, ventricular arrhythmias, and torsade de pointes, have been observed in patients receiving ketoconazole oral tablets in combination with other QT-prolonging drugs