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Auranofin (AF) and buthionine sulfoximine (BSO) co-treatment induces synergistic oxidative stress in U1 cells

10.3390/ijms16010193 172 TirumalaM

These cells exhibit high mitochondrial activity and enhanced ROS-buffering capacity, relying on the Trx system and mitophagy to establish a stable metabolic barrier against therapy-induced cell death [63]