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Well, let's just say it explains those unexpected bathroom trips that often come with high-dose oral magnesium

doi: 10.1523/JNEUROSCI.3881-15.2016 57 MontoriSDos-AnjosSMartnez-VillayandreBRegueiro-PurriosMMGonzalo-OrdenJMRuanoDet al

A better understanding of the transcriptomic changes in neuronal and non-neuronal cells induced by different CIPN-causing chemotherapy agents not only could characterize a common pathophysiological mechanism underlying CIPN, but also provides a platform to identify novel therapeutics targets and preventative strategies for CIPN

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ETC1 and ETC2 act as enhancers of TRY and CPC to facilitate the movement of TRY in cells and inhibit MBW complex formation (Esch et al., 2006