foxo4-dri senolytic animal model 2023 2024 Peptide inhibitors targeting FOXO4-p53 interactions and inducing senescent cancer cell-specific apoptosis ES2 rapidly destroys TP53-FOXO4 foci
ES2 rapidly destroys TP53 FOXO4 foci leading to TP53 mediated Download Scientific Diagram 2022 Lupus Highlight Therapeutic Targeting of Senescent Cells in Lupus, Lupus Research Program, Congressionally Directed Medical Research Programs Frontiers FOXO4 DRI regulates endothelial cell senescence via the P53 signaling pathway The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4 DRI Nature Communications Targeting the FOXO4 p53 axis by retro inverso peptide senolytic agents: a pharmacological strategy to mitigate brain aging and cognitive decline Naunyn Schmiedeberg's Archives of Pharmacology Springer Nature Link
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