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doi: 10.1038/s41467-021-21242-z 87 RuzickaTSimmetTPeskarBARingJ

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These modifications in metabolism pathways resulted in a substantial increase in the levels of 48 metabolites such as Xanthine, ascorbate, Cys-Gly, kynurenine, phenylalanine, 5-hydroxykynurenine, and others as outlined in Supplementary Figures 5A, B

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This article explores the mechanism of AOD-9604, its effects on metabolic pathways, factors influencing its activity, and the current state of scientific research