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However, the existing morphological grading system lacks standardized, clinically proven objective criteria and is intrinsically subjective, largely depending on the knowledge and interpretation of embryologists

In the POLLUX clinical trial, patients with relapsed or refractory multiple myeloma who received the combination of the anti-CD38 antibody daratumumab with lenalidomide and dexamethasone had significantly prolonged progression-free survival (PFS) relative to those who received lenalidomide and dexamethasone alone