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High (variant is assumed to have disruptive impact in the protein: stop codon gained and loss of function), low (harmless or unlikely to change protein behavior: synonymous codon), moderate (non-disruptive variant that might alter protein effectiveness: missense codon and inframe codon loss) and modifier (non-coding variants or variants affecting non-coding genes: exon variant and downstream gene variant) are parameters used by SnpEff to correlate SNPs and their putative impact on protein functioning

The 5-LOX and 12/15-LOX pathways regulate synaptic pruning and phagocytosis by microglia, affecting neurodevelopment

10.2174/0113862073258523231025095117 102 LiuY.ZhuH.ZhouW.YeQ

Antibacterial Toothpaste: Harmful, Helpful, or Harmless

Vitamin B12 can also help to prevent megaloblastic anemia, which is a blood condition that makes people severely tired and weak