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Another major confound is the common perspective within psychosocial psychiatry to consider ME/CFS as a condition triggered by excessive rest in predisposed individuals following acute triggers [17]

In a randomized clinical trial, the antioxidant astaxanthin, in combination with collagen peptides, improved facial skin elasticity and hydration and reduced matrix metalloproteinase expression while increasing endogenous collagen expression 54 , suggesting enhanced collagen homeostasis

Pretreatment with L-citrulline has been shown to significantly elevate intracellular NO concentrations ( Figure 3a ), thereby effectively attenuating pathological mitochondrial fission

Wu J, Moheimani H, Li S, Kar UK, Bonaroti J, Miller RS, et al

10.1016/j.fm.2011.07.011 Forde BM, Neville BA, ODonnell MM, Riboulet-Bisson E, Claesson MJ, Coghlan A, Ross RP, OToole PW: Genome sequences and comparative genomics of two Lactobacillus ruminis strains from the bovine and human intestinal tracts