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Similarly, in Parkinsons disease, oxidative modifications contribute to the misfolding of alpha-synuclein, leading to the formation of Lewy bodies [191, 192]

Uric Acid Uric Acid Normal Range - 0.21 - 0.42 mmol/L Aim of Urate lowering therapy is to bring uric acid levels to less than 0.3 mmol/L Risk Factors for Gout Factor which increase uric acid production are male sex, alcohol consumption, obesity, weight gain Factors which reduce renal clearance of uric acid are diuretics, low dose salicylates (aspirin), renal insufficiency

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Yao M, Wei Z, Nielsen JS et al (2024) Senolytic therapy preserves blood-brain barrier integrity and promotes microglia homeostasis in a tauopathy model

Hanno P and Dmochowski R: Status of international consensus on interstitial cystitis/bladder pain syndrome/painful bladder syndrome: 2008 snapshot