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Numerous speciesincluding fish, benthic macroinvertebrates, shrimp, crustaceans, bacteria, periphyton, and diatomshave been utilized to study the effects of heavy metal contamination in marine environments ( Penaeus indicus were found to accumulate As (0.61 ug g -1 ) and Cd (0.0.28 ug g -1 ) at levels 2 and 23 times higher, respectively, than the dorsal muscles of Mugil gulio (As: 0.32 and Cu 0.03 ug g -1 ) (Ray and Vashishth, 2024) and across various tissues within the same species (Malik and Maurya, 2014)

C R Soc Biol (Paris), 151: 1932-1935

Moreover, the cdk4 , cdk6 , and e2f1 genes show extensive gene amplification and gene mutation in various tumors

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