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For instance, the cathepsin B inhibitor E-64, when added to IVM medium, improves the developmental competence of ovum pick-up-derived immature oocytes ( Sus scrofa oocytes alters DNA methylation profiles and gene expression, thereby modifying epigenetic programming during oogenesis ( Growth hormone (GH) supplementation has also been shown to increase euploid blastocyst rates, potentially reducing aneuploidy and improving pregnancy outcomes in cases of recurrent pregnancy loss (Table 1

314 CP31398 can possibly target new synthetic mutant p53 and change its conformation in living cells

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