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Subcutaneous administration achieves 7085% bioavailability compared to 4050% for oral routes due to hepatic first-pass metabolism

Individuals who are pregnant, breastfeeding, or planning to become pregnant should avoid MIC B12 injections

Testing should occur annually or bi-annually, particularly for individuals experiencing hair loss, as vitamin D deficiency can disrupt the anagen phase of hair growth and lead to premature follicle regression

"[C]ountries may receive correct quantities overall but have insufficient cold chain capacity to accommodate deliveries, with the result that vaccines are at risk of exposure to adverse temperatures," the WHO said