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Description

CD38 deficiency has improved glucose intolerance with HFD, which could be further ameliorated by supplement of NR

NNC0090-2746 (RG7697) is a compound that has been tested in multiple preclinical and clinical studies as a dual GIPR/GLP-1R agonist [58,59,60]

TABLE 1 mRNA therapeutic Strategies

While initial attempts have achieved partial recapitulation of testicular cell interactions, these models have not yet demonstrated the capacity to support complete spermatogenesis from stem cells to mature sperm (144)