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Ketamine enhances structural plasticity in mouse mesencephalic and human iPSC-derived dopaminergic neurons via AMPAR-driven BDNF and mTOR signaling

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These cytokines may individually or synergistically stimulate CRH secretion, ultimately leading to increased glucocorticoid release, appetite suppression, and exacerbation of muscle wasting in patients

pmid:7614519

Principle: similar to the Transwell migration assay, but with a critical distinction: the upper surface of the polycarbonate membrane is coated with a matrix-like material (e.g., Matrigel or collagen) to mimic the ECM environment