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Lindgren, M., Molander, L., Verbaan, C., Lunell, E

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Another chemically induced mouse model of colitis is based on the intra-rectal administration of trinitrobenzene sulphonic acid (TNBS), which functions as a hapten (a small molecule that elicits an immune response only when attached to a larger protein) modifying autologous colonic proteins that subsequently induce a T cell-mediated response (mainly Th1)

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