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Mitochondrial diseases in humans can arise from a myriad of mutations in mitochondrial and nuclear (cellular) DNA [4]

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Correction of the DNA synthesis defect in vitamin B12 deficiency by tetrahydrofolate: evidence in favour of the methyl-folate trap hypothesis as the cause of megaloblastic anaemia in vitamin B12 deficiency

Patients should be encouraged to consume B12-rich foods, including: Meat, particularly liver and kidney Fish and shellfish Dairy products (milk, cheese, yoghurt) Eggs Fortified breakfast cereals and plant-based milk alternatives For patients following plant-based diets, fortified foods and supplementation become essential, as vitamin B12 is naturally found almost exclusively in animal products

Skin Remodeling: GHK-Cu & Stem Cell Actions Proven to increase collagen