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Therefore, inhibiting IECs death and intestinal mucosal inflammation, as well as repairing the intestinal barrier, are key therapeutic goals for IBD

10.1016/j.ecoenv.2018.07.059 Summary Keywords Benzo(a)pyrene, cardiovascular diseases, AhR, oxidative stress, inflammation, genotoxicity Citation Fu C, Li Y, Xi H, Niu Z, Chen N, Wang R, Yan Y, Gan X, Wang M, Zhang W, Zhang Y and Lv P (2022) Benzo(a)pyrene and cardiovascular diseases: An overview of pre-clinical studies focused on the underlying molecular mechanism

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The elements to consider in such a composite profiling, for a principal component analysis, could be for instance the following