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"The body has mechanisms to control most of them, including ergothioneine and glutathione, but eventually enough accrue to cause damage, which has been associated with many of the diseases of aging, like cancer, coronary heart disease and Alzheimer's." According to the researchers, who report their findings in a recent issue of Food Chemistry, the amounts of ergothioneine and glutathione in mushrooms vary by species with the porcini species, a wild variety, containing the highest amount of the two compounds among the 13 species tested

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In an injectable it is supplied as reduced glutathione (GSH) , the active form, which is chemically distinct from its oxidized dimer

Butterfield DA, Sultana R

Like all the active ingredients used in cosmetics, even for glutathione, the formulation science will always matter more than the percentage of active