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doi: 10.1093/brain/awac222 31 MuraiTMaruyamaYMioKNishiyamaHSugaMSatoC

Among LOX inhibitors, Zileuton (A-64077), a LOX-5 inhibitor, reduces oxidative stress by regulating ROS levels in retinal pigment epithelial (RPE) cells, offering potential for retinal disease treatment (Liu et al., 2015