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This affects the parts of your brain responsible for hunger, sending a signal to your brain that you are full

Severe but Not Moderate Vitamin B12 Deficiency impairs lipid profile, induces adiposity, and leads to adverse gestational outcome in female C57BL/6 mice

This is usually the case for elderly populations, those following a vegetarian or vegan diet, and people with disordered eating or chronic diseases that lead to malnutrition

The NNMT inhibition approach targets what researchers call the "metabolic flexibility" of cells