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Decades of daily smoking cause progressive and often irreversible damage to the chest and lungs. Long term exposure to tobacco smoke leads to chronic inflammation, loss of lung elasticity, reduced oxygen exchange, and Cigarette Smoking and Inflammation: Cellular and Molecular Mechanisms PMC Pilot study shows even short term 'vaping' causes inflammation in non smokers Health Tip on Smoking Can Cause Colitis, Crohn's Disease Tobacco Smoke Induces and Alters Immune Responses in the Lung Triggering Inflammation, Allergy, Asthma and Other Lung Diseases: A Mechanistic Review

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