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Journal of Biological Chemistry (2000) 275, 3590835913

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DeFronzo RA

Phosphorylation sites with missing values in more than 50% of samples were filtered out and the following key parameters were used: weight = 0, statistic = area.under.RES, output.score.type = NES, nperm = 1000 and min.overlap = 5

However, high B12 levels in the blood can be a sign of underlying kidney or liver disease, indicating that these organs are struggling to get rid of excess B12