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This contributes to a more stable secondary structure under laboratory conditions

therefore, a strategy involving direct activation of the cells associated with angiogenesis has recently been attempted [13,14,15]

O peptdeo atua principalmente por meio da modulao da via do fator de crescimento endotelial vascular (VEGF) e do sistema NO

doi:10.1016/j.yjmcc.2022.08.002

Several molecular mechanisms have been identified that may explain resistance and increased invasion after anti-angiogenic therapy in glioma, including mesenchymal transition of tumor cells, up-regulation of pro-angiogenic factors, activation of MET and up-regulation of MMPs [293,294,295,296]