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Description

Levofloxacin works by inhibiting bacterial type II topoisomerases, particularly the enzymes topoisomerase IV (Topo IV) and bacterial DNA gyrase

[Google Scholar] 146.Silva-Carvalho R, Baltazar F, Almeida-Aguiar C

Gibson PR, Varney J, Malakar S, Muir JG

Stem Cells 12 (10), 11841195

These specificity groups spanned a continuum from acidophilic kinases selecting negatively charged residues surrounding their Tyr sites (including FAK (encoded by PTK2