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On an immunomodulatory level, anti-inflammatory factors secreted by the amniotic membrane (e.g., SLPI/elafin) synergize with MenSC-derived paracrine cytokines such as IDO, PGE 2 , and TGF-, promoting the polarization of macrophages from the pro-inflammatory M1 phenotype to the regenerative M2 phenotype

Oxidative cell death in cancer: mechanisms and therapeutic opportunities

When ketones cover most of the brains energy demands, the remaining glucose can be more efficiently utilized for other purposes, such as the synthesis of alanine and glutamate, glycogenesis, and antioxidant protection [20]

MicroRNA 10a marks regulatory T cells

In summary, gut dysbiosis would be related to the onset and progression of NDDs in several ways