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In summary, the beneficial effects of elevated H 2 S under pathophysiological conditions, or following pharmacological intervention, may be due in large part to the antioxidant consequences of the generation of persulfides

MNA cells rely on an elevated antioxidant response through the Xc-/glutathione (GSH) pathway to scavenge lipid hydroperoxides, a by-product formed from excess H 2 O 2 (11, 12)