Connecting to other gene-expression datasets Using GSEA, sets of genes reported to change with COPD-related phenotypes or with TGF treatment in other gene-expression studies were examined in a ranked list of genes ordered from most induced in severe emphysema to most repressed in severe emphysema by the t-statistic of the Lm coefficient in the linear mixed-effects model
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As such, it is possible that our results may have been different if samples were in storage for a greater duration of time
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