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In addition, we discuss the newly elucidated strategies by which Mtb manipulates the host molecular regulatory machinery of innate immunity, including the intranuclear regulatory machinery, the ubiquitin system, and cellular intrinsic immune components

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TMEM164 has also been suggested to induce autophagy, resulting in ferritin, GPX4, and lipid droplet degradation 136

The Academy also recommends the analysis of biochemical data, in-depth physical examination, and inquiries about personal and family history, among other aspects