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This break prevents tolerance buildup and allows the neurological effects to consolidate

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We first compared the performance of CloneSelect CT, using enhanced green fluorescent protein (EGFP) as a reporter, with three other CRISPRa-based systems reported previously (CaTCH, ClonMapper and CaTCH alternative) 29,31 and two other setups (low-copy CRISPRa and high-copy CRISPRa) that we prepared for this study

A few commenters indicated that the Patient Population-Level Management and any associated data analysis could be completed by the practice and did not necessarily need to be completed by the practitioner