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For people with type 2 diabetes or prediabetic metabolic profiles, this dual action addresses both the weight and the underlying metabolic dysfunction simultaneously

Nonetheless, low IGF-1 circulating levels are also associated with reduced insulin sensitivity [207], glucose intolerance, and T2D [207, 208, 214]

J Occup Environ Med

For example, excess growth hormone causes insulin resistance and hyperglycemia, whereas IGF1 has insulin-like effects that reduce blood glucose levels and has been used experimentally to treat both type 1 and type 2 diabetes

If you're in a risk group reduced food intake on GLP-1s, plant-based diet, long-term metformin or PPI use, over 50 and fatigue is dragging you down, checking your B12 is one of the highest-ROI moves you can make