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A C20 fatty-diacid moiety enables reversible serum-albumin binding and a markedly extended half-life relative to native incretins, and the balanced dual-receptor activity is what distinguishes it from single GLP-1 agonists like GLP-1 (Sema) and from the triple agonist GLP-3 (Reta)

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acquired the data, performed analyses and prepared figures

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