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For example, Bluebird Bio offers rebates for its beta-thalassemia and SCD CGTs.[70] Payers may receive up to 80% of the up-front price if a CGT recipient is hospitalized for a serious manifestation of the disease the CGT is expected to solve, for two or three years after treatment.[71] The optimal time horizon depends in part on how quickly treatment nonresponse manifests, which may itself be uncertain when a CGT is newly launched

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