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Concurrent investigations employing cutting-edge kidney-on-a-chip architectures have revealed that renal parenchymal tissues demonstrate remarkable adaptive responsiveness to gut-derived metabolic signaling through modulation of transport protein expression repertoires, representing an elegant adaptive mechanism meticulously calibrated to preserve systemic metabolic equilibrium (Jochems et al., 2019

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Chen S, Shi J, Yu D, Dong S (2024) Advance on combination therapy strategies based on biomedical nanotechnology induced ferroptosis for cancer therapeutics