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Frontiers in Plant Science 7: 862

The chemical reaction involves the deprotonation of C4 in the A ring of the steroid substrate, thereby enabling the double bond between C5 and C6 to isomerize to a double bond between C4 and C5 (Figure 2)

Antonoff MB , Shelstad R, Reihsen T, Schmitz, C, Chipman J, Maddaus MA, DCunha J

High expression of HTR1D correlates with poor prognosis in patients with gastric cancer (GC), and knockdown of HTR1D inhibits tumor progression by inducing ferroptosis [125]