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While primarily studied for its anti-aging properties through telomerase activation, epitalon's sleep relevance stems from its proposed effects on the pineal gland and melatonin production

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Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

Mitochondrial dysfunction amplifies reactive oxygen species (ROS) production, inducing DNA damage and hyperactivating PARP-1 [105]